Retinal Advanced

ISDIN Unique dual-phase night serum for visibly rejuvenated skin


Product Overview:

Rejuvenate, Renew, and sooth with ISDIN Retinal Advanced. This advanced dual-phase night serum is formulated to correct lines and wrinkles while promoting cellular turnover for firmer and more youthful appearing skin. Added ingredients also work to hydrate and moisturize. This unique formula combines the power of retinaldehyde, melatonin and bakuchiol with Soothing Complex that combine just prior to application. Product is non-comedogenic, mineral oil free, and ideal for use on all skin types. Users report noticeably renewed skin after 4 weeks of use!


  • Nighttime anti-aging serum
  • Corrects fine line and wrinkles
  • Boost cellular turnover
  • Improves skin elasticity and firmness
  • Create more youthful complexion


  • Product Type: Anti-aging serum
  • Size: 1.7 oz
  • Ideal for these skin types: All Skin Types
  • Main Ingredients: Retinaldehyde, Melatonin, Bakuchiol, Soothing Complex
  • Area of use: Face, Neck, Chest

How To Use:

Apply the product at night to clean and dry skin. Gently press the pump twice to release the appropriate amount of serum into the palm of your hand. Mix the serum thoroughly. Massage the serum evenly onto your face and neck, taking care to avoid the delicate eye area. The following morning, it is crucial to apply a broad-spectrum sunscreen.

If this is your first time using a retinoid, we recommend a gradual approach to acclimate your skin. Start by applying it three nights a week. In the second week, increase the frequency to four nights. If you experience no discomfort by the third week, you can safely increase application to seven nights a week.


Aqua (Water), Dimethicone, Dibutyl Adipate, Niacinamide, Isoamyl Laurate, Lauryl PEG/PPG-18/18 Methicone, Glycerin, Propanediol, Dimethicone/Vinyl Dimethicone Crosspolymer, Alcohol Denat., Bakuchiol, 1,2-Hexanediol, Pentylene Glycol, Caprylic/Capric Triglyceride, Ethylcellulose, Hydroxyacetophenone, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, 4-T-Butylcyclohexanol, Caprylyl Glycol, Parfum (Fragrance), Sodium Acrylates Crosspolymer-2, Polyacrylate Crosspolymer-6, Vigna Aconitifolia Seed Extract, Tocopheryl Acetate, Tocopherol, Citric Acid, Xanthan Gum, Maltodextrin, Melatonin, Retinal (Retinaldehyde), Silica, Disodium EDTA, Phospholipids, Synthetic Fluorphlogopite, CI 77891 (Titanium Dioxide), Ascorbic Acid, T-Butyl Alcohol, Rosmarinus Officinalis (Rosemary) Leaf Extract, Palmitoyl Tetrapeptide-7, Tin Oxide, Chrysin.

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